William Harper
William Harper may refer to:
- William Harper (composer) (born 1949), composer and photographer
- William Harper (South Carolina) (1790–1847), US Senator from South Carolina
- William Allen Harper, JFK assassination witness
- William Claude Harper (born 1944), American jewelry artist
- William Edmund Harper (1878–1940), Canadian astronomer
- William Rainey Harper (1856–1906), first president of the University of Chicago
- Bill Harper (1898–1989), Scottish football (soccer) goalkeeper
- Billy Harper, jazz saxophonist
- Willie Harper, former American football linebacker
- Will Harper, minor Eastenders character
- William Harper, Jr., pioneer aviator with the Wright brothers